5C46
Crystal structure of an engineered construct of phosphatidylinositol 4 kinase III beta in complex with GTP gamma S loaded Rab11
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (E) | Phosphatidylinositol 4-kinase beta | polymer | 529 | 60683.8 | 1 | UniProt (Q9UBF8) Pfam (PF21245) Pfam (PF00454) | Homo sapiens (Human) | PtdIns 4-kinase beta,NPIK |
| 2 | B (F) | Ras-related protein Rab-11A | polymer | 219 | 24691.8 | 1 | UniProt (P62491) Pfam (PF00071) | Homo sapiens (Human) | Rab-11,YL8 |
| 3 | C, D (E) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E (F) | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE | non-polymer | 539.2 | 1 | Chemie (GSP) | |||
| 5 | F (F) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | G, H (E, F) | water | water | 18.0 | 4 | Chemie (HOH) |
Sequence modifications
E: 121 - 287 (UniProt: Q9UBF8)
E: 288 - 507 (UniProt: Q9UBF8)
E: 508 - 784 (UniProt: Q9UBF8)
F: 1 - 216 (UniProt: P62491)
| PDB | External Database | Details |
|---|---|---|
| Gly 117 | - | expression tag |
| Ser 118 | - | expression tag |
| His 119 | - | expression tag |
| Met 120 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 294 | Ser 294 | engineered mutation |
F: 1 - 216 (UniProt: P62491)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Leu 70 | Gln 70 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 85375.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 755.7 | |
| All* | Total formula weight | 86131.3 |
