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5C1M

Crystal structure of active mu-opioid receptor bound to the agonist BU72

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Mu-type opioid receptorpolymer29633728.31UniProt (P42866)
Pfam (PF00001)
Mus musculus (Mouse)MOR-1
2B
(B)
Nanobody 39polymer12513669.01Lama glama
3C, D
(A)
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoatenon-polymer356.52Chemie (OLC)
4E
(A)
CHOLESTEROLnon-polymer386.71Chemie (CLR)
5F
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
6G, H
(A)
HEXAETHYLENE GLYCOLnon-polymer282.32Chemie (P6G)
7I
(A)
(2R,3S,3aR,5aR,6R,11bR,11cS)-3a-methoxy-3,14-dimethyl-2-phenyl-2,3,3a,6,7,11c-hexahydro-1H-6,11b-(epiminoethano)-3,5a-methanonaphtho[2,1-g]indol-10-olnon-polymer428.61Chemie (VF1)
8J, K
(A, B)
waterwater18.094Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight47397.3
Non-Polymers*Number of molecules7
Total formula weight2187.9
All*Total formula weight49585.2
*Water molecules are not included.

237992

PDB entries from 2025-06-25

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