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5C0Y

Crystal structure of the Rrp6 catalytic domain bound to poly(U) RNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Exosome complex exonuclease RRP6polymer40247072.42UniProt (Q12149)
Pfam (PF01612)
Pfam (PF00570)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)Ribosomal RNA-processing protein 6
2C, D
(D, C)
poly U RNApolymer154547.52synthetic construct
3E
(B)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4F, G, H, I
(A, B, D, C)
waterwater18.0588Chemie (HOH)
Sequence modifications
A, B: 122 - 518 (UniProt: Q12149)
PDBExternal DatabaseDetails
Gly 117-expression tag
Pro 118-expression tag
Asp 119-expression tag
Ser 120-expression tag
Met 121-expression tag
Asn 296Asp 296engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight103239.9
Non-Polymers*Number of molecules1
Total formula weight24.3
All*Total formula weight103264.2
*Water molecules are not included.

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PDB entries from 2025-06-18

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