5C0Y
Crystal structure of the Rrp6 catalytic domain bound to poly(U) RNA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000175 | molecular_function | 3'-5'-RNA exonuclease activity |
| A | 0000467 | biological_process | exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| A | 0008408 | molecular_function | 3'-5' exonuclease activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000175 | molecular_function | 3'-5'-RNA exonuclease activity |
| B | 0000467 | biological_process | exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| B | 0008408 | molecular_function | 3'-5' exonuclease activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 601 |
| Chain | Residue |
| B | ASP238 |
| B | LEU239 |
| B | GLU240 |
| B | GLN255 |
| B | ASP365 |
| D | U15 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 332 |
| Details | Domain: {"description":"3'-5' exonuclease","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 160 |
| Details | Domain: {"description":"HRDC","evidences":[{"source":"PROSITE-ProRule","id":"PRU00328","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16882719","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2HBL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2HBM","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16882719","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2HBM","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16882719","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2HBK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2HBL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2HBM","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17330950","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
