5BY6

Crystal structure of Trichinella spiralis thymidylate synthase complexed with dUMP

Replaces:  4G9U

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Thymidylate synthase	polymer	307	35544.4	4	UniProt (Q9NDD3) Pfam (PF00303)	Trichinella spiralis (Trichina worm)
2	E, K, L, N (A, B, C, D)	2'-DEOXYURIDINE 5'-MONOPHOSPHATE	non-polymer		308.2	4	Chemie (UMP)
3	F (A)	2,3-DIHYDROXY-1,4-DITHIOBUTANE	non-polymer		154.3	1	Chemie (DTT)
4	G, H, I, J, M... (A, C, D)	GLYCEROL	non-polymer		92.1	8	Chemie (GOL)
5	R, S, T, U (A, B, C, D)	water	water		18.0	862	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	142177.8
Non-Polymers*	Number of molecules	13
	Total formula weight	2123.7
All*	Total formula weight	144301.5

*Water molecules are not included.