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5BXV

eIF4E complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, C)
Eukaryotic translation initiation factor 4Epolymer19222331.32UniProt (P63073)
Pfam (PF01652)
Mus musculus (Mouse)mRNA cap-binding protein,eIF-4F 25 kDa subunit
2B, D
(B, D)
Eukaryotic translation initiation factor 4E-binding protein 1polymer444840.52UniProt (Q13541)
Pfam (PF05456)
Homo sapiens (Human)eIF4E-binding protein 1,Phosphorylated heat- and acid-stable protein regulated by insulin 1,PHAS-I
3E, F
(A, C)
7-METHYL-GUANOSINE-5'-TRIPHOSPHATEnon-polymer538.22Chemie (MGP)
4G, H, I, J
(A, B, C, D)
waterwater18.0218Chemie (HOH)
Sequence modifications
A, C: 27 - 217 (UniProt: P63073)
PDBExternal DatabaseDetails
Gly 26-expression tag
B, D: 43 - 84 (UniProt: Q13541)
PDBExternal DatabaseDetails
Gly 41-expression tag
Glu 42-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight54343.6
Non-Polymers*Number of molecules2
Total formula weight1076.4
All*Total formula weight55420.1
*Water molecules are not included.

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PDB entries from 2026-01-21

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