5BRH
Crystal structure of Trypanosoma cruzi glucokinase in complex with inhibitor DBT-GlcN
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Glucokinase 1, putative | polymer | 381 | 42226.6 | 2 | UniProt (Q4E4E1) Pfam (PF02685) In PDB | Trypanosoma cruzi (strain CL Brener) | |
2 | A, B | 2-deoxy-2-({[(1,1-dioxido-1-benzothiophen-2-yl)methoxy]carbonyl}amino)-beta-D-glucopyranose | non-polymer | 401.4 | 2 | Chemie (4V3) | |||
3 | water | water | 18.0 | 201 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 367 (UniProt: Q4E4E1)
PDB | External Database | Details |
---|---|---|
Met -13 | - | initiating methionine |
Gly -12 | - | expression tag |
Arg -11 | - | expression tag |
Gly -10 | - | expression tag |
Ser -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
Gly -2 | - | expression tag |
Met -1 | - | expression tag |
Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 84453.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 802.8 | |
All* | Total formula weight | 85256.1 |