5BRH
Crystal structure of Trypanosoma cruzi glucokinase in complex with inhibitor DBT-GlcN
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004340 | molecular_function | glucokinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005536 | molecular_function | D-glucose binding |
| A | 0006096 | biological_process | glycolytic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0051156 | biological_process | glucose 6-phosphate metabolic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004340 | molecular_function | glucokinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005536 | molecular_function | D-glucose binding |
| B | 0006096 | biological_process | glycolytic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0051156 | biological_process | glucose 6-phosphate metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue 4V3 A 500 |
| Chain | Residue |
| A | GLY93 |
| A | GLU236 |
| A | HOH655 |
| A | HOH656 |
| B | PHE337 |
| A | PRO94 |
| A | PRO103 |
| A | PHE104 |
| A | ASN105 |
| A | ASN130 |
| A | ASP131 |
| A | GLY188 |
| A | GLU207 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue 4V3 B 500 |
| Chain | Residue |
| A | PHE337 |
| A | PHE339 |
| B | GLY93 |
| B | PRO94 |
| B | PRO103 |
| B | PHE104 |
| B | ASN105 |
| B | ASN130 |
| B | ASP131 |
| B | GLY186 |
| B | GLU207 |
| B | GLU236 |
| B | HOH640 |
