5BRH
Crystal structure of Trypanosoma cruzi glucokinase in complex with inhibitor DBT-GlcN
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0004340 | molecular_function | glucokinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0005536 | molecular_function | D-glucose binding |
A | 0006096 | biological_process | glycolytic process |
A | 0016740 | molecular_function | transferase activity |
A | 0051156 | biological_process | glucose 6-phosphate metabolic process |
B | 0000166 | molecular_function | nucleotide binding |
B | 0004340 | molecular_function | glucokinase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0005536 | molecular_function | D-glucose binding |
B | 0006096 | biological_process | glycolytic process |
B | 0016740 | molecular_function | transferase activity |
B | 0051156 | biological_process | glucose 6-phosphate metabolic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 13 |
Details | binding site for residue 4V3 A 500 |
Chain | Residue |
A | GLY93 |
A | GLU236 |
A | HOH655 |
A | HOH656 |
B | PHE337 |
A | PRO94 |
A | PRO103 |
A | PHE104 |
A | ASN105 |
A | ASN130 |
A | ASP131 |
A | GLY188 |
A | GLU207 |
site_id | AC2 |
Number of Residues | 13 |
Details | binding site for residue 4V3 B 500 |
Chain | Residue |
A | PHE337 |
A | PHE339 |
B | GLY93 |
B | PRO94 |
B | PRO103 |
B | PHE104 |
B | ASN105 |
B | ASN130 |
B | ASP131 |
B | GLY186 |
B | GLU207 |
B | GLU236 |
B | HOH640 |