5BPU
Crystal structure of Norrin, a Wnt signalling activator, Crystal Form I
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Norrin | polymer | 122 | 13614.7 | 6 | UniProt (Q00604) Pfam (PF00007) | Homo sapiens (Human) | Norrie disease protein,X-linked exudative vitreoretinopathy 2 protein |
| 2 | G (H) | (GGL)EEEEEE | polymer | 7 | 921.8 | 1 | synthetic construct | ||
| 3 | H (I) | (GGL)EEE | polymer | 4 | 534.5 | 1 | synthetic construct | ||
| 4 | I, J, K, L, M... (A, B, C, D, E...) | water | water | 18.0 | 164 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 25 - 133 (UniProt: Q00604)
| PDB | External Database | Details |
|---|---|---|
| Gly 22 | - | expression tag |
| Pro 23 | - | expression tag |
| Gly 24 | - | expression tag |
| Gly 134 | - | expression tag |
| Thr 135 | - | expression tag |
| Glu 136 | - | expression tag |
| Thr 137 | - | expression tag |
| Ser 138 | - | expression tag |
| Gln 139 | - | expression tag |
| Val 140 | - | expression tag |
| Ala 141 | - | expression tag |
| Pro 142 | - | expression tag |
| Ala 143 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 83144.5 | |
| All* | Total formula weight | 83144.5 |
