5B4X
Crystal structure of the ApoER2 ectodomain in complex with the Reelin R56 fragment
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Reelin | polymer | 725 | 81786.0 | 2 | UniProt (Q60841) Pfam (PF21471) In PDB | Mus musculus (Mouse) | Reeler protein |
2 | B, D | Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor, isoform CRA_e | polymer | 570 | 63649.1 | 2 | UniProt (D3DQ39) Pfam (PF07645) Pfam (PF00058) Pfam (PF00057) Pfam (PF14670) UniProt (by SIFTS) (Q14114) In PDB | Homo sapiens (Human) | LRP-8,Apolipoprotein E receptor 2 |
3 | A, B, C, D | CALCIUM ION | non-polymer | 40.1 | 16 | Chemie (CA) | |||
4 | A, B, C, D | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) |
Sequence modifications
A, C: 1948 - 2662 (UniProt: Q60841)
B, D: 41 - 606 (UniProt: D3DQ39)
PDB | External Database | Details |
---|---|---|
Gly 1946 | - | expression tag |
Arg 1947 | - | expression tag |
Ala 2101 | Cys 2101 | engineered mutation |
Arg 2663 | - | expression tag |
Leu 2664 | - | expression tag |
Glu 2665 | - | expression tag |
Asn 2666 | - | expression tag |
Leu 2667 | - | expression tag |
Tyr 2668 | - | expression tag |
Phe 2669 | - | expression tag |
Gln 2670 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ser 40 | - | expression tag |
Ala 607 | - | expression tag |
Ser 608 | - | expression tag |
Ser 609 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 290870.3 | |
Non-Polymers* | Number of molecules | 21 |
Total formula weight | 1747.3 | |
All* | Total formula weight | 292617.6 |