5B1S

Crystal structure of Trypanosoma cruzi spermidine synthase in complex with 2-(2-fluorophenyl)ethanamine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Spermidine synthase, putative	polymer	304	34103.7	4	UniProt (Q4DA73) Pfam (PF17284) Pfam (PF01564)	Trypanosoma cruzi strain CL Brener
2	E, G, I, K (A, B, C, D)	5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE	non-polymer		356.4	4	Chemie (S4M)
3	F, H, J, L (A, B, C, D)	2-(2-fluorophenyl)ethanamine	non-polymer		139.2	4	Chemie (BSX)
4	M, N, O, P (A, B, C, D)	water	water		18.0	583	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 296 (UniProt: Q4DA73)

PDB	External Database	Details
Met -7	-	expression tag
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	136414.9
Non-Polymers*	Number of molecules	8
	Total formula weight	1982.5
All*	Total formula weight	138397.3

*Water molecules are not included.