5AWM

The Crystal Structure of JNK from Drosophila melanogaster Reveals an Evolutionarily Conserved Topology with that of Mammalian JNK Proteins.

Replaces:  4M3A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Stress-activated protein kinase JNK	polymer	394	45509.5	1	UniProt (P92208) Pfam (PF00069)	Drosophila melanogaster (Fruit fly)	dJNK,Protein basket
2	B (A)	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	1	Chemie (ANP)
3	C, D (A)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	E (A)	water	water		18.0	143	Chemie (HOH)

Sequence modifications

A: 1 - 372 (UniProt: P92208)

PDB	External Database	Details
Met -21	-	expression tag
Gly -20	-	expression tag
Ser -19	-	expression tag
Ser -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
Ser -11	-	expression tag
Ser -10	-	expression tag
Gly -9	-	expression tag
Leu -8	-	expression tag
Val -7	-	expression tag
Pro -6	-	expression tag
Arg -5	-	expression tag
Gly -4	-	expression tag
Ser -3	-	expression tag
His -2	-	expression tag
Arg -1	-	expression tag
Thr 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	45509.5
Non-Polymers*	Number of molecules	3
	Total formula weight	554.8
All*	Total formula weight	46064.4

*Water molecules are not included.