5AVI
Crystal structure of LXRalpha in complex with tert-butyl benzoate analog, compound 4
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Oxysterols receptor LXR-alpha | polymer | 283 | 32866.4 | 2 | UniProt (Q13133) Pfam (PF00104) In PDB | Homo sapiens (Human) | Liver X receptor alpha,Nuclear receptor subfamily 1 group H member 3 |
2 | B, D | Nuclear receptor coactivator 1 | polymer | 25 | 2806.2 | 2 | UniProt (Q15788) Pfam (PF08832) In PDB | Homo sapiens | NCoA-1,Class E basic helix-loop-helix protein 74,bHLHe74,Protein Hin-2,RIP160,Renal carcinoma antigen NY-REN-52,Steroid receptor coactivator 1,SRC-1 |
3 | A, C | tert-butyl 2-[[4-[ethanoyl(methyl)amino]phenoxy]methyl]-5-(trifluoromethyl)benzoate | non-polymer | 423.4 | 2 | Chemie (4KM) | |||
4 | water | water | 18.0 | 72 | Chemie (HOH) |
Sequence modifications
A, C: 182 - 447 (UniProt: Q13133)
PDB | External Database | Details |
---|---|---|
Met 165 | - | initiating methionine |
Lys 166 | - | expression tag |
His 167 | - | expression tag |
Gln 168 | - | expression tag |
His 169 | - | expression tag |
Gln 170 | - | expression tag |
His 171 | - | expression tag |
Gln 172 | - | expression tag |
His 173 | - | expression tag |
Gln 174 | - | expression tag |
His 175 | - | expression tag |
Gln 176 | - | expression tag |
His 177 | - | expression tag |
Gln 178 | - | expression tag |
Gln 179 | - | expression tag |
Pro 180 | - | expression tag |
Leu 181 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 71345.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 846.9 | |
All* | Total formula weight | 72192.0 |