5AOX
Human Alu RNA retrotransposition complex in the ribosome-stalling conformation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN | polymer | 85 | 9980.5 | 2 | UniProt (P49458) Pfam (PF05486) | HOMO SAPIENS (HUMAN) | SRP9 |
| 2 | B, E (B, E) | SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN | polymer | 94 | 10555.3 | 2 | UniProt (P37108) Pfam (PF02290) | HOMO SAPIENS (HUMAN) | SRP14,18 KDA ALU RNA-BINDING PROTEIN, SRP14 |
| 3 | C, F (C, F) | ALU JO CONSENSUS RNA | polymer | 87 | 28238.8 | 2 | SYNTHETIC CONSTRUCT | ||
| 4 | G, M (C, F) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 5 | H, N (C, F) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 6 | I (C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 7 | J, K, L, O (C, F) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 8 | P, Q, R, S, T... (A, B, C, D, E...) | water | water | 18.0 | 381 | Chemie (HOH) |
Sequence modifications
A, D: 2 - 86 (UniProt: P49458)
B, E: 2 - 95 (UniProt: P37108)
| PDB | External Database | Details |
|---|---|---|
| Ser 48 | Cys 48 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 2 | Val 2 | engineered mutation |
| Ala 3 | Leu 3 | engineered mutation |
| Met 4 | Leu 4 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 97549.1 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 513.6 | |
| All* | Total formula weight | 98062.6 |
