5AOX

Human Alu RNA retrotransposition complex in the ribosome-stalling conformation

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0005047	molecular_function	signal recognition particle binding
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005785	cellular_component	signal recognition particle receptor complex
A	0005786	cellular_component	signal recognition particle, endoplasmic reticulum targeting
A	0005829	cellular_component	cytosol
A	0006614	biological_process	SRP-dependent cotranslational protein targeting to membrane
A	0006617	biological_process	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition
A	0008312	molecular_function	7S RNA binding
A	0045900	biological_process	negative regulation of translational elongation
A	0048500	cellular_component	signal recognition particle
A	1990904	cellular_component	ribonucleoprotein complex
B	0005786	cellular_component	signal recognition particle, endoplasmic reticulum targeting
B	0006614	biological_process	SRP-dependent cotranslational protein targeting to membrane
B	0008312	molecular_function	7S RNA binding
B	0030942	molecular_function	endoplasmic reticulum signal peptide binding
B	0048500	cellular_component	signal recognition particle
D	0003723	molecular_function	RNA binding
D	0005047	molecular_function	signal recognition particle binding
D	0005515	molecular_function	protein binding
D	0005737	cellular_component	cytoplasm
D	0005785	cellular_component	signal recognition particle receptor complex
D	0005786	cellular_component	signal recognition particle, endoplasmic reticulum targeting
D	0005829	cellular_component	cytosol
D	0006614	biological_process	SRP-dependent cotranslational protein targeting to membrane
D	0006617	biological_process	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition
D	0008312	molecular_function	7S RNA binding
D	0045900	biological_process	negative regulation of translational elongation
D	0048500	cellular_component	signal recognition particle
D	1990904	cellular_component	ribonucleoprotein complex
E	0005786	cellular_component	signal recognition particle, endoplasmic reticulum targeting
E	0006614	biological_process	SRP-dependent cotranslational protein targeting to membrane
E	0008312	molecular_function	7S RNA binding
E	0030942	molecular_function	endoplasmic reticulum signal peptide binding
E	0048500	cellular_component	signal recognition particle

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ACT C 1001

Chain	Residue
B	THR61
B	HOH2027
C	U24
C	G25

---

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 C 1011

Chain	Residue
C	C3
C	C4

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PEG C 1051

Chain	Residue
B	HOH2048
C	A27
C	A28
C	HOH2155
C	HOH2156
B	TYR33
B	SER68
B	VAL70

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG C 1101

Chain	Residue
C	A57
C	G59
C	HOH2110
C	HOH2111
C	HOH2112
C	HOH2113

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG C 1111

Chain	Residue
C	U17
C	G41
C	HOH2046
C	HOH2047
C	HOH2086

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG C 1131

Chain	Residue
C	C108
C	HOH2011
C	HOH2012
C	HOH2015
C	HOH2141
C	HOH2142

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACT F 1001

Chain	Residue
E	THR61
F	U24
F	G25

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 F 1011

Chain	Residue
F	C3
F	C4
F	HOH2047

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG F 1131

Chain	Residue
F	C108
F	HOH2007
F	HOH2010
F	HOH2061
F	HOH2062
F	HOH2066

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---