5AGI
Crystal structure of the LeuRS editing domain of Candida albicans Mutant K510A in complex with the adduct formed by AN2690-AMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | POTENTIAL CYTOSOLIC LEUCYL TRNA SYNTHETASE | polymer | 261 | 29438.5 | 1 | UniProt (Q5A9A4) Pfam (PF00133) UniProt (by SIFTS) (A0A1D8PS12) | CANDIDA ALBICANS | |
| 2 | B (A) | [(6-AMINO-9H-PURIN-9-YL)-[5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1-BENZOXABOROLE]-4'YL]METHYL DIHYDROGEN PHOSPHATE | non-polymer | 480.1 | 1 | Chemie (ANZ) | |||
| 3 | C, D (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) PubChem (753) | |||
| 4 | E (A) | water | water | 18.0 | 249 | Chemie (HOH) |
Sequence modifications
A: 280 - 530 (UniProt: Q5A9A4)
| PDB | External Database | Details |
|---|---|---|
| Met 278 | - | expression tag |
| Gly 279 | - | expression tag |
| Leu 531 | - | expression tag |
| Glu 532 | - | expression tag |
| His 533 | - | expression tag |
| His 534 | - | expression tag |
| His 535 | - | expression tag |
| His 536 | - | expression tag |
| His 537 | - | expression tag |
| His 538 | - | expression tag |
| Ala 510 | Lys 510 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29438.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 664.3 | |
| All* | Total formula weight | 30102.8 |
