5AGI

Crystal structure of the LeuRS editing domain of Candida albicans Mutant K510A in complex with the adduct formed by AN2690-AMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	POTENTIAL CYTOSOLIC LEUCYL TRNA SYNTHETASE	polymer	261	29438.5	1	UniProt (Q5A9A4)	CANDIDA ALBICANS
2	B (A)	[(6-AMINO-9H-PURIN-9-YL)-[5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1-BENZOXABOROLE]-4'YL]METHYL DIHYDROGEN PHOSPHATE	non-polymer		480.1	1	Chemie (ANZ)
3	C, D (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4	E (A)	water	water		18.0	249	Chemie (HOH)

Sequence modifications

A: 280 - 530 (UniProt: Q5A9A4)

PDB	External Database	Details
Met 278	-	expression tag
Gly 279	-	expression tag
Leu 531	-	expression tag
Glu 532	-	expression tag
His 533	-	expression tag
His 534	-	expression tag
His 535	-	expression tag
His 536	-	expression tag
His 537	-	expression tag
His 538	-	expression tag
Ala 510	Lys 510	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	29438.5
Non-Polymers*	Number of molecules	3
	Total formula weight	664.3
All*	Total formula weight	30102.8

*Water molecules are not included.