5AGI
Crystal structure of the LeuRS editing domain of Candida albicans Mutant K510A in complex with the adduct formed by AN2690-AMP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0002161 | molecular_function | aminoacyl-tRNA editing activity |
| A | 0004823 | molecular_function | leucine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006429 | biological_process | leucyl-tRNA aminoacylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE ANZ A 600 |
| Chain | Residue |
| A | ALA315 |
| A | VAL412 |
| A | ASP418 |
| A | SER419 |
| A | LYS483 |
| A | GOL1532 |
| A | HOH2024 |
| A | HOH2125 |
| A | HOH2126 |
| A | HOH2128 |
| A | HOH2133 |
| A | THR316 |
| A | HOH2138 |
| A | HOH2249 |
| A | LEU317 |
| A | ARG318 |
| A | THR321 |
| A | ARG366 |
| A | VAL403 |
| A | LEU404 |
| A | LYS407 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 1532 |
| Chain | Residue |
| A | LEU317 |
| A | ARG318 |
| A | ARG366 |
| A | LYS483 |
| A | TYR487 |
| A | ANZ600 |
| A | HOH2207 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 1533 |
| Chain | Residue |
| A | ARG286 |
| A | LYS309 |
| A | TYR311 |
| A | TYR501 |
| A | ASP504 |
| A | HOH2097 |
