5A46
FGFR1 in complex with dovitinib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B | polymer | 386 | 43619.9 | 2 | UniProt (D3DSX2) Pfam (PF07714) UniProt (by SIFTS) (P11362) | HOMO SAPIENS (HUMAN) | FGFR1 |
| 2 | C, D, E, I (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 3 | F, J (A, B) | 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one | non-polymer | 392.4 | 2 | Chemie (38O) | |||
| 4 | G, H, K (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 5 | L, M (A, B) | water | water | 18.0 | 226 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 87239.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1321.3 | |
| All* | Total formula weight | 88561.2 |
