5A3C
Crystal structure of the ADP-ribosylating sirtuin (SirTM) from Streptococcus pyogenes in complex with NAD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SIR2 FAMILY PROTEIN | polymer | 303 | 35156.6 | 1 | UniProt (Q1JGN6) UniProt (by SIFTS) (P0DN71) | STREPTOCOCCUS PYOGENES | ADP-RIBOSYLATING SIRTUIN, SIRTM |
| 2 | B, C, D (A) | GLYCINE | non-polymer | 75.1 | 3 | Chemie (GLY) | |||
| 3 | E (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | F (A) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 1 | Chemie (NAD) | |||
| 5 | G, H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 6 | I (A) | water | water | 18.0 | 157 | Chemie (HOH) |
Sequence modifications
A: 1 - 293 (UniProt: Q1JGN6)
| PDB | External Database | Details |
|---|---|---|
| Met -9 | - | expression tag |
| Gly -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35156.6 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1078.2 | |
| All* | Total formula weight | 36234.8 |
