4ZX2
Co-crystal structures of PP5 in complex with 5-methyl-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein phosphatase 5 | polymer | 333 | 37887.0 | 1 | UniProt (P53041) Pfam (PF08321) Pfam (PF00149) | Homo sapiens (Human) | PP5,Protein phosphatase T,PPT |
| 2 | B, C (A) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | D (A) | (1S,2R,3S,4R,5S)-5-methyl-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid | non-polymer | 200.2 | 1 | Chemie (4TE) | |||
| 4 | E (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 5 | F (A) | (4R)-2-METHYLPENTANE-2,4-DIOL | non-polymer | 118.2 | 1 | Chemie (MRD) | |||
| 6 | G (A) | water | water | 18.0 | 344 | Chemie (HOH) |
Sequence modifications
A: 169 - 499 (UniProt: P53041)
| PDB | External Database | Details |
|---|---|---|
| Gly 167 | - | expression tag |
| Ala 168 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37887.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 546.4 | |
| All* | Total formula weight | 38433.4 |
