4ZVF

Crystal structure of GGDEF domain of the E. coli DosC - form II (GTP-alpha-S-bound)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Diguanylate cyclase DosC	polymer	172	19900.6	1	UniProt (P0AA89) Pfam (PF00990) In PDB	Escherichia coli K-12	DGC,Direct oxygen-sensing cyclase
2	A	GUANOSINE-5'-RP-ALPHA-THIO-TRIPHOSPHATE	non-polymer		539.2	1	Chemie (GAV)
3	A	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
4	A	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
5		water	water		18.0	172	Chemie (HOH)

Sequence modifications

A: 297 - 460 (UniProt: P0AA89)

PDB	External Database	Details
Leu 461	-	expression tag
Glu 462	-	expression tag
His 463	-	expression tag
His 464	-	expression tag
His 465	-	expression tag
His 466	-	expression tag
His 467	-	expression tag
His 468	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	19900.6
Non-Polymers*	Number of molecules	5
	Total formula weight	743.5
All*	Total formula weight	20644.1

*Water molecules are not included.