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4ZVF

Crystal structure of GGDEF domain of the E. coli DosC - form II (GTP-alpha-S-bound)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Diguanylate cyclase DosCpolymer17219900.61UniProt (P0AA89)
Pfam (PF00990)
Escherichia coli K-12DGC,Direct oxygen-sensing cyclase
2B
(A)
GUANOSINE-5'-RP-ALPHA-THIO-TRIPHOSPHATEnon-polymer539.21Chemie (GAV)
3C, D
(A)
CALCIUM IONnon-polymer40.12Chemie (CA)
4E, F
(A)
1,2-ETHANEDIOLnon-polymer62.12Chemie (EDO)
5G
(A)
waterwater18.0172Chemie (HOH)
Sequence modifications
A: 297 - 460 (UniProt: P0AA89)
PDBExternal DatabaseDetails
Leu 461-expression tag
Glu 462-expression tag
His 463-expression tag
His 464-expression tag
His 465-expression tag
His 466-expression tag
His 467-expression tag
His 468-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight19900.6
Non-Polymers*Number of molecules5
Total formula weight743.5
All*Total formula weight20644.1
*Water molecules are not included.

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PDB entries from 2025-06-11

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