4ZRJ
Structure of Merlin-FERM and CTD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Merlin | polymer | 320 | 37730.6 | 1 | UniProt (P35240) Pfam (PF09379) Pfam (PF00373) Pfam (PF09380) | Homo sapiens (Human) | Moesin-ezrin-radixin-like protein,Neurofibromin-2,Schwannomerlin,Schwannomin |
| 2 | B (B) | Merlin | polymer | 90 | 10749.2 | 1 | UniProt (P35240) Pfam (PF00769) | Homo sapiens (Human) | Moesin-ezrin-radixin-like protein,Neurofibromin-2,Schwannomerlin,Schwannomin |
| 3 | C, D, E, F, G... (A) | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) | |||
| 4 | K, L (A, B) | water | water | 18.0 | 107 | Chemie (HOH) |
Sequence modifications
B: 506 - 595 (UniProt: P35240)
| PDB | External Database | Details |
|---|---|---|
| Asp 518 | Ser 518 | engineered mutation |
| Trp 585 | Ala 585 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 48479.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 736.8 | |
| All* | Total formula weight | 49216.6 |
