Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003779 | molecular_function | actin binding |
| A | 0008092 | molecular_function | cytoskeletal protein binding |
| B | 0003779 | molecular_function | actin binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 601 |
| Chain | Residue |
| A | HIS84 |
| A | ASP85 |
| A | LYS294 |
| B | ASP518 |
| B | ILE521 |
| B | GLU522 |
| B | LYS525 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 602 |
| Chain | Residue |
| A | TYR244 |
| A | ARG249 |
| A | LEU250 |
| A | PRO252 |
| B | LYS573 |
| A | GLU215 |
| A | ASP237 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 603 |
| Chain | Residue |
| A | PRO19 |
| A | LYS269 |
| A | SER288 |
| A | GOL605 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 604 |
| Chain | Residue |
| A | TRP60 |
| A | PHE62 |
| A | GLY63 |
| A | LYS99 |
| A | PHE100 |
| A | VAL318 |
| A | GLN319 |
| A | GLN320 |
| A | HOH728 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 605 |
| Chain | Residue |
| A | ASP70 |
| A | GLU107 |
| A | SER288 |
| A | LYS289 |
| A | LEU290 |
| A | ARG291 |
| A | GOL603 |
| B | GLU524 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 606 |
| Chain | Residue |
| A | THR67 |
| A | LYS69 |
| A | ASP70 |
| A | ARG310 |
| A | ARG311 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 607 |
| Chain | Residue |
| A | TYR101 |
| A | PRO102 |
| A | GLU103 |
| A | GLN212 |
| A | TYR217 |
| A | LEU239 |
| A | HOH703 |
| A | HOH723 |
| B | LYS573 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 608 |
| Chain | Residue |
| A | LYS130 |
| A | MET216 |
| A | TYR221 |
| A | ARG249 |
| A | LYS312 |
| A | ALA313 |
| A | ASP314 |
| A | HOH746 |
Functional Information from PROSITE/UniProt
| site_id | PS00660 |
| Number of Residues | 31 |
| Details | FERM_1 FERM domain signature 1. WLkmdKkVldHd.Vskeepvt.FhflakFYpeN |
| Chain | Residue | Details |
| A | TRP74-ASN104 | |
| site_id | PS00661 |
| Number of Residues | 30 |
| Details | FERM_2 FERM domain signature 2. YaehrgrardEAemeYLki.AqdLemYGvNY |
| Chain | Residue | Details |
| A | TYR192-TYR221 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 289 |
| Details | Domain: {"description":"FERM","evidences":[{"source":"PROSITE-ProRule","id":"PRU00084","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine; by PAK","evidences":[{"source":"PubMed","id":"17081983","evidenceCode":"ECO:0007744"}]} |
