4ZM9
Crystal structure of circularly permuted human asparaginase-like protein 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Isoaspartyl peptidase/L-asparaginase | polymer | 327 | 33767.2 | 4 | UniProt (Q7L266) Pfam (PF01112) | Homo sapiens (Human) | Asparaginase-like protein 1,Beta-aspartyl-peptidase,Isoaspartyl dipeptidase,L-asparagine amidohydrolase |
| 2 | E, L, M, Q, X... (A, B, C, D) | SODIUM ION | non-polymer | 23.0 | 7 | Chemie (NA) | |||
| 3 | AA, F, N, R (D, A, B, C) | GLYCINE | non-polymer | 75.1 | 4 | Chemie (GLY) | |||
| 4 | CA, G, H, I, J... (D, A, B, C) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 10 | Chemie (BME) | |||
| 5 | K, W (A, C) | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | non-polymer | 154.3 | 2 | Chemie (DTT) | |||
| 6 | BA, O (D, B) | CITRATE ANION | non-polymer | 189.1 | 2 | Chemie (FLC) | |||
| 7 | DA, EA, FA, GA (A, B, C, D) | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 308 (UniProt: Q7L266)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | linker |
| His 154 | - | expression tag |
| His 154 | - | expression tag |
| His 154 | - | expression tag |
| His 154 | - | expression tag |
| His 154 | - | expression tag |
| His 154 | - | expression tag |
| Met 154 | - | SEE REMARK 999 |
| Gly 309 | - | linker |
| Ala 310 | - | linker |
| Gly 311 | - | linker |
| Ser 312 | - | linker |
| Gly 313 | - | linker |
| Ala 314 | - | linker |
| Gly 315 | - | linker |
| Ser 316 | - | linker |
| Gly 317 | - | linker |
| Ala 318 | - | linker |
| Gly 319 | - | linker |
| Gly 320 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 135068.7 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 1929.2 | |
| All* | Total formula weight | 136997.9 |
