4ZL4
Plasmepsin V from Plasmodium vivax bound to a transition state mimetic (WEHI-842)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Aspartic protease PM5 | polymer | 444 | 50582.4 | 2 | UniProt (Q6PRR9) Pfam (PF14543) Pfam (PF00026) UniProt (by SIFTS) (A5K302) | Plasmodium vivax | |
| 2 | C, K (A, B) | N-[(benzyloxy)carbonyl]-O-carbamimidamido-L-homoseryl-N-{(3S,4S)-3-hydroxy-6-methyl-1-oxo-1-[(2-phenylethyl)amino]heptan-4-yl}-L-valinamide | non-polymer | 669.8 | 2 | BIRD (PRD_002168) Chemie (4PK) | |||
| 3 | D, E, F, L, M... (A, B) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 4 | G, H, I, J, P... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 5 | R (B) | (2R)-1-[(2R)-2-(2-methoxyethoxy)propoxy]propan-2-amine | non-polymer | 191.3 | 1 | Chemie (4PF) | |||
| 6 | S, T (A, B) | water | water | 18.0 | 284 | Chemie (HOH) |
Sequence modifications
A, B: 35 - 476 (UniProt: Q6PRR9)
| PDB | External Database | Details |
|---|---|---|
| Gly 33 | - | expression tag |
| Thr 34 | - | expression tag |
| Val 276 | Ile 276 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 101164.7 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2575.7 | |
| All* | Total formula weight | 103740.5 |
