4ZFF
Dual-acting Fab 5A12 in complex with VEGF
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, H) | Fragment antigen binding (Fab) 5A12 Heavy chain | polymer | 228 | 24231.2 | 2 | Homo sapiens (Human) | ||
| 2 | B, F (B, L) | Fragment antigen binding (Fab) 5A12 Light chain | polymer | 215 | 23296.9 | 2 | Homo sapiens (Human) | ||
| 3 | C, D (C, D) | Vascular endothelial growth factor A | polymer | 99 | 11649.4 | 2 | UniProt (P15692) Pfam (PF00341) | Homo sapiens (Human) | VEGF-A,Vascular permeability factor,VPF |
| 4 | G (L) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | H, I, J, K, L... (A, B, C, D, H...) | water | water | 18.0 | 429 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 118355.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 96.1 | |
| All* | Total formula weight | 118451.1 |
