4ZER

Crystal structure of the Onc112 antimicrobial peptide bound to the Thermus thermophilus 70S ribosome

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, CB (1A, 2A)	23s ribosomal RNA	polymer	2915	948007.6	2	GenBank (55771382)	Thermus thermophilus HB8
2	B, DB (1B, 2B)	5s ribosomal RNA	polymer	120	38882.2	2	GenBank (48271)	Thermus thermophilus HB8
3	C, EB (1D, 2D)	50S ribosomal protein L2	polymer	275	30401.4	2	UniProt (Q72I07) Pfam (PF00181) Pfam (PF03947) UniProt (by SIFTS) (P60405)	Thermus thermophilus HB8
4	D, FB (1E, 2E)	50S ribosomal protein L3	polymer	204	22250.0	2	UniProt (Q72I04) Pfam (PF00297) UniProt (by SIFTS) (Q5SHN8)	Thermus thermophilus HB8
5	E, GB (1F, 2F)	50S ribosomal protein L4	polymer	203	22512.0	2	UniProt (Q5SHN9) Pfam (PF00573)	Thermus thermophilus HB8	L1e
6	F, HB (1G, 2G)	50S ribosomal protein L5	polymer	181	20930.4	2	UniProt (Q5SHQ0) Pfam (PF00281) Pfam (PF00673)	Thermus thermophilus HB8
7	G, IB (1H, 2H)	50S ribosomal protein L6	polymer	174	18980.2	2	UniProt (Q72I19) Pfam (PF00347) UniProt (by SIFTS) (P0DOY8)	Thermus thermophilus HB8
8	H, JB (1I, 2I)	50S ribosomal protein L9	polymer	147	16293.1	2	UniProt (Q5SLQ1) Pfam (PF01281) Pfam (PF03948)	Thermus thermophilus HB8
9	I, KB (1N, 2N)	50S ribosomal protein L13	polymer	140	15927.9	2	UniProt (Q72IN1) Pfam (PF00572) UniProt (by SIFTS) (P60488)	Thermus thermophilus HB8
10	J, LB (1O, 2O)	50S ribosomal protein L14	polymer	122	13323.6	2	UniProt (Q5SHP8) Pfam (PF00238)	Thermus thermophilus HB8
11	K, MB (1P, 2P)	50S ribosomal protein L15	polymer	149	16248.1	2	UniProt (Q72I23) Pfam (PF00828) UniProt (by SIFTS) (Q5SHQ7)	Thermus thermophilus HB8
12	L, NB (1Q, 2Q)	50S ribosomal protein L16	polymer	141	15993.9	2	UniProt (P60489) Pfam (PF00252)	Thermus thermophilus HB8
13	M, OB (1R, 2R)	50S ribosomal protein L17	polymer	118	13750.1	2	UniProt (Q72I33) Pfam (PF01196) UniProt (by SIFTS) (Q9Z9H5)	Thermus thermophilus HB8
14	N, PB (1S, 2S)	50S ribosomal protein L18	polymer	110	12437.6	2	UniProt (Q72I20) Pfam (PF00861) UniProt (by SIFTS) (Q5SHQ4)	Thermus thermophilus HB8
15	O, QB (1T, 2T)	50S ribosomal protein L19	polymer	131	15503.0	2	UniProt (P60490) Pfam (PF01245)	Thermus thermophilus HB8
16	P, RB (1U, 2U)	50S ribosomal protein L20	polymer	116	13591.0	2	UniProt (Q72L76) Pfam (PF00453) UniProt (by SIFTS) (P60491)	Thermus thermophilus HB8
17	Q, SB (1V, 2V)	50S ribosomal protein L21	polymer	101	11069.2	2	UniProt (Q72HR2) Pfam (PF00829) UniProt (by SIFTS) (P60492)	Thermus thermophilus HB8
18	R, TB (1W, 2W)	50S ribosomal protein L22	polymer	112	12678.9	2	UniProt (Q72I09) Pfam (PF00237) UniProt (by SIFTS) (Q5SHP3)	Thermus thermophilus HB8
19	S, UB (1X, 2X)	50S ribosomal protein L23	polymer	95	10646.6	2	UniProt (Q72I06) Pfam (PF00276) UniProt (by SIFTS) (Q5SHP0)	Thermus thermophilus HB8
20	T, VB (1Y, 2Y)	50S ribosomal protein L24	polymer	107	11726.3	2	UniProt (Q72I15) Pfam (PF00467) Pfam (PF17136) UniProt (by SIFTS) (Q5SHP9)	Thermus thermophilus HB8
21	U, WB (1Z, 2Z)	50S ribosomal protein L25	polymer	203	22851.2	2	UniProt (Q72IA7) Pfam (PF01386) Pfam (PF14693) UniProt (by SIFTS) (Q5SHZ1)	Thermus thermophilus HB8	General stress protein CTC
22	V, XB (10, 20)	50S ribosomal protein L27	polymer	77	8689.0	2	UniProt (P60493) Pfam (PF01016)	Thermus thermophilus HB8
23	W, YB (11, 21)	50S ribosomal protein L28	polymer	97	10873.0	2	UniProt (P60494) Pfam (PF00830)	Thermus thermophilus HB8
24	X, ZB (12, 22)	50S ribosomal protein L29	polymer	70	8485.1	2	UniProt (Q72I12) Pfam (PF00831) UniProt (by SIFTS) (Q5SHP6)	Thermus thermophilus HB8
25	AC, Y (13, 23)	50S ribosomal protein L30	polymer	59	6667.9	2	UniProt (Q72I22) Pfam (PF00327) UniProt (by SIFTS) (Q5SHQ6)	Thermus thermophilus HB8
26	BC, Z (14, 24)	50S ribosomal protein L31	polymer	69	8086.3	2	UniProt (Q72JR0) Pfam (PF01197) UniProt (by SIFTS) (Q5SJE1)	Thermus thermophilus HB8
27	AA, CC (15, 25)	50S ribosomal protein L32	polymer	59	6590.9	2	UniProt (P80339) Pfam (PF01783)	Thermus thermophilus HB8
28	BA, DC (16, 26)	50S ribosomal protein L33	polymer	53	6501.7	2	UniProt (Q72GW3) Pfam (PF00471) UniProt (by SIFTS) (P35871)	Thermus thermophilus HB8
29	CA, EC (17, 27)	50S ribosomal protein L34	polymer	48	5975.3	2	UniProt (P80340) Pfam (PF00468)	Thermus thermophilus HB8
30	DA, FC (18, 28)	50S ribosomal protein L35	polymer	64	7375.0	2	UniProt (Q72L77) Pfam (PF01632) UniProt (by SIFTS) (Q5SKU1)	Thermus thermophilus HB8
31	EA, GC (19, 29)	50S ribosomal protein L36	polymer	37	4435.4	2	UniProt (Q72I28) Pfam (PF00444) UniProt (by SIFTS) (Q5SHR2)	Thermus thermophilus HB8
32	FA, HC (1a, 2a)	16s ribosomal RNA	polymer	1521	493863.6	2	GenBank (155076)	Thermus thermophilus HB8
33	GA, IC (1b, 2b)	30S ribosomal protein S2	polymer	231	26646.9	2	UniProt (P62662) Pfam (PF00318) UniProt (by SIFTS) (P80371)	Thermus thermophilus HB8
34	HA, JC (1c, 2c)	30S ribosomal protein S3	polymer	206	22862.4	2	UniProt (P62663) Pfam (PF07650) Pfam (PF00189) UniProt (by SIFTS) (P80372)	Thermus thermophilus HB8
35	IA, KC (1d, 2d)	30S ribosomal protein S4	polymer	208	24242.3	2	UniProt (P62664) Pfam (PF00163) Pfam (PF01479) UniProt (by SIFTS) (P80373)	Thermus thermophilus HB8
36	JA, LC (1e, 2e)	30S ribosomal protein S5	polymer	148	16144.8	2	UniProt (P62665) Pfam (PF00333) Pfam (PF03719) UniProt (by SIFTS) (Q5SHQ5)	Thermus thermophilus HB8
37	KA, MC (1f, 2f)	30S ribosomal protein S6	polymer	100	11917.7	2	UniProt (P62666) Pfam (PF01250) UniProt (by SIFTS) (Q5SLP8)	Thermus thermophilus HB8
38	LA, NC (1g, 2g)	30S ribosomal protein S7	polymer	155	17919.8	2	UniProt (P62667) Pfam (PF00177) UniProt (by SIFTS) (P17291)	Thermus thermophilus HB8
39	MA, OC (1h, 2h)	30S ribosomal protein S8	polymer	137	15737.4	2	UniProt (P62668) Pfam (PF00410) UniProt (by SIFTS) (P0DOY9)	Thermus thermophilus HB8
40	NA, PC (1i, 2i)	30S ribosomal protein S9	polymer	127	14279.4	2	UniProt (P80374) Pfam (PF00380)	Thermus thermophilus HB8
41	OA, QC (1j, 2j)	30S ribosomal protein S10	polymer	97	11170.0	2	UniProt (P62653) Pfam (PF00338) UniProt (by SIFTS) (Q5SHN7)	Thermus thermophilus HB8
42	PA, RC (1k, 2k)	30S ribosomal protein S11	polymer	114	12032.7	2	UniProt (P62654) Pfam (PF00411) UniProt (by SIFTS) (P80376)	Thermus thermophilus HB8
43	QA, SC (1l, 2l)	30S ribosomal protein S12	polymer	122	13650.2	2	UniProt (P61941) Pfam (PF00164) UniProt (by SIFTS) (Q5SHN3)	Thermus thermophilus HB8
44	RA, TC (1m, 2m)	30S ribosomal protein S13	polymer	116	13237.4	2	UniProt (P62655) Pfam (PF00416) UniProt (by SIFTS) (P80377)	Thermus thermophilus HB8
45	SA, UC (1n, 2n)	30S ribosomal protein S14 type Z	polymer	60	7027.5	2	UniProt (P62656) Pfam (PF00253) UniProt (by SIFTS) (P0DOY6)	Thermus thermophilus HB8
46	TA, VC (1o, 2o)	30S ribosomal protein S15	polymer	88	10447.2	2	UniProt (P62657) Pfam (PF00312) UniProt (by SIFTS) (Q5SJ76)	Thermus thermophilus HB8
47	UA, WC (1p, 2p)	30S ribosomal protein S16	polymer	82	9795.4	2	UniProt (P62238) Pfam (PF00886) UniProt (by SIFTS) (Q5SJH3)	Thermus thermophilus HB8
48	VA, XC (1q, 2q)	30S ribosomal protein S17	polymer	99	11722.9	2	UniProt (Q5SHP7) Pfam (PF00366) UniProt (by SIFTS) (P0DOY7)	Thermus thermophilus HB8
49	WA, YC (1r, 2r)	30S ribosomal protein S18	polymer	68	7897.5	2	UniProt (P62659) Pfam (PF01084) UniProt (by SIFTS) (Q5SLQ0)	Thermus thermophilus HB8
50	XA, ZC (1s, 2s)	30S ribosomal protein S19	polymer	83	9456.0	2	UniProt (P62660) Pfam (PF00203) UniProt (by SIFTS) (Q5SHP2)	Thermus thermophilus HB8
51	AD, YA (1t, 2t)	30S ribosomal protein S20	polymer	98	10876.1	2	UniProt (P80380) Pfam (PF01649)	Thermus thermophilus HB8
52	BD, ZA (1u, 2u)	30S ribosomal protein Thx	polymer	23	2831.3	2	UniProt (Q5SIH3) Pfam (PF17070)	Thermus thermophilus HB8	S31
53	AB, CD (1x, 2x)	tRNA met	polymer	76	24541.7	2	GenBank (745369752)	Escherichia coli K-12
54	BB, DD (1y, 2y)	Onc112	polymer	19	2396.8	2		Oncopeltus fasciatus
55	ED, FD (A, B)	mRNA	polymer	27	8754.2	2		Thermus thermophilus HB8
56	AAA, AAB, AAC, ABA, ABB... (1A, 1a, 2A, 1e, 2D...)	MAGNESIUM ION	non-polymer		24.3	2302	Chemie (MG)	Thermus thermophilus HB8
57	BMA, ODC (1A, 2A)	UNKNOWN ATOM OR ION	non-polymer		351.6	2	Chemie (UNX)
58	CMA, PCB (1A, 1a)	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	2	Chemie (MPD)
59	UOA (1B)	ARGININE	non-polymer		175.2	1	Chemie (ARG)
60	AOC, ESA, GSA, HDB, IGC... (2n, 14, 15, 1n, 2Y...)	ZINC ION	non-polymer		65.4	12	Chemie (ZN)
61	TCB, TNC (1d, 2d)	IRON/SULFUR CLUSTER	non-polymer		351.6	2	Chemie (SF4)
62	MDC (2A)	POTASSIUM ION	non-polymer		39.1	1	Chemie (K)
63	APC, AQC, ARC, BPC, BQC... (1T, 2B, 2r, 1U, 2D...)	water	water		18.0	3865	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	110
	Total formula weight	4354269.6
Non-Polymers*	Number of molecules	2322
	Total formula weight	58592.2
All*	Total formula weight	4412861.8

*Water molecules are not included.