4ZDA

Crystal structure of isocitrate dehydrogenase in complex with isocitrate and Mn from M. smegmatis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Isocitrate dehydrogenase (NADP) Icd2	polymer	767	85581.3	6	UniProt (A0QSZ3) Pfam (PF03971)	Mycobacterium smegmatis	Isocitrate dehydrogenase,NADP-dependent
2	G, I, K, M, O... (A, B, C, D, E...)	MANGANESE (II) ION	non-polymer		54.9	6	Chemie (MN)
3	H, J, L, N, P... (A, B, C, D, E...)	ISOCITRIC ACID	non-polymer		192.1	6	Chemie (ICT)

Sequence modifications

A, B, C, D, E, F: 1 - 743 (UniProt: A0QSZ3)

PDB	External Database	Details
Pro 744	-	expression tag
Arg 745	-	expression tag
Tyr 746	-	expression tag
Pro 747	-	expression tag
Tyr 748	-	expression tag
Asp 749	-	expression tag
Val 750	-	expression tag
Pro 751	-	expression tag
Asp 752	-	expression tag
Tyr 753	-	expression tag
Ala 754	-	expression tag
Lys 755	-	expression tag
Leu 756	-	expression tag
Ala 757	-	expression tag
Ala 758	-	expression tag
Ala 759	-	expression tag
Leu 760	-	expression tag
Glu 761	-	expression tag
His 762	-	expression tag
His 763	-	expression tag
His 764	-	expression tag
His 765	-	expression tag
His 766	-	expression tag
His 767	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	513488.0
Non-Polymers*	Number of molecules	12
	Total formula weight	1482.4
All*	Total formula weight	514970.4

*Water molecules are not included.