4ZDA
Crystal structure of isocitrate dehydrogenase in complex with isocitrate and Mn from M. smegmatis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004450 | molecular_function | isocitrate dehydrogenase (NADP+) activity |
| A | 0006097 | biological_process | glyoxylate cycle |
| A | 0006099 | biological_process | tricarboxylic acid cycle |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004450 | molecular_function | isocitrate dehydrogenase (NADP+) activity |
| B | 0006097 | biological_process | glyoxylate cycle |
| B | 0006099 | biological_process | tricarboxylic acid cycle |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0004450 | molecular_function | isocitrate dehydrogenase (NADP+) activity |
| C | 0006097 | biological_process | glyoxylate cycle |
| C | 0006099 | biological_process | tricarboxylic acid cycle |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0004450 | molecular_function | isocitrate dehydrogenase (NADP+) activity |
| D | 0006097 | biological_process | glyoxylate cycle |
| D | 0006099 | biological_process | tricarboxylic acid cycle |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0004450 | molecular_function | isocitrate dehydrogenase (NADP+) activity |
| E | 0006097 | biological_process | glyoxylate cycle |
| E | 0006099 | biological_process | tricarboxylic acid cycle |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0004450 | molecular_function | isocitrate dehydrogenase (NADP+) activity |
| F | 0006097 | biological_process | glyoxylate cycle |
| F | 0006099 | biological_process | tricarboxylic acid cycle |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue MN A 801 |
| Chain | Residue |
| A | ASP352 |
| A | ASP551 |
| A | ASP555 |
| A | ICT802 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue ICT A 802 |
| Chain | Residue |
| A | MET260 |
| A | ASP352 |
| A | TYR422 |
| A | ARG550 |
| A | ASP551 |
| A | ALA585 |
| A | MN801 |
| A | SER134 |
| A | ASN137 |
| A | ARG141 |
| A | ARG147 |
| A | LYS257 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue MN B 801 |
| Chain | Residue |
| B | ASP352 |
| B | ASP551 |
| B | ASP555 |
| B | ICT802 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | binding site for residue ICT B 802 |
| Chain | Residue |
| B | SER134 |
| B | ASN137 |
| B | ARG141 |
| B | ARG147 |
| B | LYS257 |
| B | MET260 |
| B | ASP352 |
| B | TYR422 |
| B | ARG550 |
| B | ASP551 |
| B | ALA585 |
| B | MN801 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue MN C 801 |
| Chain | Residue |
| C | ASP352 |
| C | ASP551 |
| C | ASP555 |
| C | ICT802 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | binding site for residue ICT C 802 |
| Chain | Residue |
| C | SER134 |
| C | ASN137 |
| C | ARG141 |
| C | ARG147 |
| C | LYS257 |
| C | ASP352 |
| C | TYR422 |
| C | ARG550 |
| C | ASP551 |
| C | ALA585 |
| C | MN801 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue MN D 801 |
| Chain | Residue |
| D | ASP352 |
| D | ASP551 |
| D | ASP555 |
| D | ICT802 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | binding site for residue ICT D 802 |
| Chain | Residue |
| D | SER134 |
| D | ASN137 |
| D | ARG141 |
| D | ARG147 |
| D | LYS257 |
| D | MET260 |
| D | ASP352 |
| D | TYR422 |
| D | ARG550 |
| D | ASP551 |
| D | MN801 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue MN E 801 |
| Chain | Residue |
| E | ASP352 |
| E | ASP551 |
| E | ASP555 |
| E | ICT802 |
| site_id | AD1 |
| Number of Residues | 12 |
| Details | binding site for residue ICT E 802 |
| Chain | Residue |
| E | SER134 |
| E | ASN137 |
| E | ARG141 |
| E | ARG147 |
| E | LYS257 |
| E | MET260 |
| E | ASP352 |
| E | TYR422 |
| E | ARG550 |
| E | ASP551 |
| E | ALA585 |
| E | MN801 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue MN F 801 |
| Chain | Residue |
| F | ASP352 |
| F | ASP551 |
| F | ASP555 |
| F | ICT802 |
| site_id | AD3 |
| Number of Residues | 12 |
| Details | binding site for residue ICT F 802 |
| Chain | Residue |
| F | SER134 |
| F | ASN137 |
| F | ARG141 |
| F | ARG147 |
| F | LYS257 |
| F | MET260 |
| F | ASP352 |
| F | TYR422 |
| F | ARG550 |
| F | ASP551 |
| F | ALA585 |
| F | MN801 |
