4ZBW
Crystal structure of death effector domain of Caspase8 in Homo Sapiens
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Caspase-8 | polymer | 190 | 22488.9 | 2 | UniProt (Q14790) Pfam (PF01335) In PDB | Homo sapiens (Human) | CASP-8,Apoptotic cysteine protease,Apoptotic protease Mch-5,CAP4,FADD-homologous ICE/ced-3-like protease,FADD-like ICE,FLICE,ICE-like apoptotic protease 5,MORT1-associated ced-3 homolog,MACH |
| 2 | water | water | 18.0 | 248 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 188 (UniProt: Q14790)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Met 1 | - | expression tag |
| Ala 122 | Phe 181 | engineered mutation |
| Asp 128 | Ile 187 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 44977.8 | |
| All* | Total formula weight | 44977.8 |
