4ZBW
Crystal structure of death effector domain of Caspase8 in Homo Sapiens
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0006915 | biological_process | apoptotic process |
| A | 0042981 | biological_process | regulation of apoptotic process |
| B | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0006915 | biological_process | apoptotic process |
| B | 0042981 | biological_process | regulation of apoptotic process |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by autocatalytic cleavage => ECO:0000269|PubMed:8962078, ECO:0000269|PubMed:9184224 |
| Chain | Residue | Details |
| A | LEU157 | |
| B | LEU157 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:O89110 |
| Chain | Residue | Details |
| A | SER129 | |
| A | LEU152 | |
| B | SER129 | |
| B | LEU152 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:O89110 |
| Chain | Residue | Details |
| A | ALA165 | |
| B | ALA165 |
