4Z8D
Antibacterial FabH Inhibitors with Validated Mode of Action in Haemophilus Influenzae by in vitro resistance mutation mapping
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | polymer | 317 | 33547.0 | 2 | UniProt (P0A6R2) Pfam (PF08545) Pfam (PF08541) UniProt (by SIFTS) (P0A6R0) | Escherichia coli O157:H7 | 3-oxoacyl-[acyl-carrier-protein] synthase III,Beta-ketoacyl-ACP synthase III,KAS III |
| 2 | C, E (A, B) | trans-4-[({[(2-chlorobenzyl)oxy]carbonyl}amino)methyl]cyclohexanecarboxylic acid | non-polymer | 325.8 | 2 | Chemie (4LB) | |||
| 3 | D, F (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 310 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 67094.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 843.7 | |
| All* | Total formula weight | 67937.8 |
