4Z7B
Structure of the enzyme-product complex resulting from TDG action on a GfC mismatch
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | G/T mismatch-specific thymine DNA glycosylase | polymer | 204 | 23070.7 | 1 | UniProt (Q13569) Pfam (PF03167) | Homo sapiens (Human) | Thymine-DNA glycosylase,hTDG |
| 2 | B (C) | DNA (28-MER) | polymer | 28 | 8646.6 | 1 | synthetic construct | ||
| 3 | C (D) | DNA (28-MER) | polymer | 28 | 8473.4 | 1 | synthetic construct | ||
| 4 | D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | E, F (A) | ACETIC ACID | non-polymer | 60.1 | 2 | Chemie (ACY) | |||
| 6 | G, H, I (A, C, D) | water | water | 18.0 | 143 | Chemie (HOH) |
Sequence modifications
A: 111 - 308 (UniProt: Q13569)
| PDB | External Database | Details |
|---|---|---|
| Gly 105 | - | expression tag |
| Ser 106 | - | expression tag |
| His 107 | - | expression tag |
| Met 108 | - | expression tag |
| Ala 109 | - | expression tag |
| Ser 110 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 40190.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 182.2 | |
| All* | Total formula weight | 40372.8 |
