4Z32

Crystal Structure of the FERM-SH2 Domains of Jak2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Tyrosine-protein kinase JAK2	polymer	497	57681.6	8	UniProt (O60674) Pfam (PF18379) Pfam (PF18377) Pfam (PF17887) Pfam (PF21990) In PDB	Homo sapiens (Human)	Janus kinase 2,JAK-2
2		water	water		18.0	12	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H: 31 - 516 (UniProt: O60674)

PDB	External Database	Details
Gly 30	-	expression tag
Leu 517	-	expression tag
Glu 518	-	expression tag
His 519	-	expression tag
His 520	-	expression tag
His 521	-	expression tag
His 522	-	expression tag
His 523	-	expression tag
His 524	-	expression tag
His 525	-	expression tag
His 526	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	461453.2
All*	Total formula weight	461453.2

*Water molecules are not included.