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4Z0I

Crystal structure of a tetramer of GluA2 ligand binding domains bound with glutamate at 1.45 Angstrom resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BGlutamate receptor 2,Glutamate receptor 2polymer26329221.72UniProt (P19491)
Pfam (PF10613)
Pfam (PF00060)
In PDB
Rattus norvegicus (norway Rat)GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2,GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2
2A, BGLUTAMIC ACIDnon-polymer147.12Chemie (GLU)
3A, BPHOSPHATE IONnon-polymer95.06Chemie (PO4)
4ATETRAETHYLENE GLYCOLnon-polymer194.21Chemie (PG4)
5ADI(HYDROXYETHYL)ETHERnon-polymer106.11Chemie (PEG)
6waterwater18.0850Chemie (HOH)
Sequence modifications
A, B: 3 - 117 (UniProt: P19491)
PDBExternal DatabaseDetails
Gly 1-expression tag
Ala 2-expression tag
A, B: 120 - 263 (UniProt: P19491)
PDBExternal DatabaseDetails
Gly 118-linker
Thr 119-linker
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight58443.4
Non-Polymers*Number of molecules10
Total formula weight1164.4
All*Total formula weight59607.8
*Water molecules are not included.

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PDB entries from 2024-07-17

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