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4Z0I

Crystal structure of a tetramer of GluA2 ligand binding domains bound with glutamate at 1.45 Angstrom resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Glutamate receptor 2,Glutamate receptor 2polymer26329221.72UniProt (P19491)
Pfam (PF10613)
Pfam (PF00060)
Rattus norvegicus (norway Rat)GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2,GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2
2C, I
(A, B)
GLUTAMIC ACIDnon-polymer147.12Chemie (GLU)
3D, E, F, J, K...
(A, B)
PHOSPHATE IONnon-polymer95.06Chemie (PO4)
4G
(A)
TETRAETHYLENE GLYCOLnon-polymer194.21Chemie (PG4)
5H
(A)
DI(HYDROXYETHYL)ETHERnon-polymer106.11Chemie (PEG)
6M, N
(A, B)
waterwater18.0850Chemie (HOH)
Sequence modifications
A, B: 3 - 117 (UniProt: P19491)
PDBExternal DatabaseDetails
Gly 1-expression tag
Ala 2-expression tag
A, B: 120 - 263 (UniProt: P19491)
PDBExternal DatabaseDetails
Gly 118-linker
Thr 119-linker
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight58443.4
Non-Polymers*Number of molecules10
Total formula weight1164.4
All*Total formula weight59607.8
*Water molecules are not included.

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PDB entries from 2025-06-11

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