Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue GLU A 301 |
| Chain | Residue |
| A | TYR61 |
| A | TYR220 |
| A | HOH467 |
| A | HOH507 |
| A | HOH513 |
| A | PRO89 |
| A | LEU90 |
| A | THR91 |
| A | ARG96 |
| A | GLY141 |
| A | SER142 |
| A | THR143 |
| A | GLU193 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue PO4 A 302 |
| Chain | Residue |
| A | SER140 |
| A | LYS144 |
| A | ARG148 |
| A | PEG306 |
| A | HOH410 |
| A | HOH418 |
| A | HOH419 |
| A | HOH509 |
| A | HOH593 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 A 303 |
| Chain | Residue |
| A | HIS46 |
| A | LYS240 |
| A | HOH470 |
| A | HOH473 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue PO4 A 304 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | binding site for residue PG4 A 305 |
| Chain | Residue |
| A | GLY1 |
| A | LYS117 |
| A | GLU201 |
| A | GLN202 |
| A | TYR256 |
| A | CYS261 |
| A | GLY262 |
| A | SER263 |
| A | HOH447 |
| A | HOH495 |
| A | HOH523 |
| A | HOH650 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue PEG A 306 |
| Chain | Residue |
| A | ASP139 |
| A | LYS144 |
| A | SER168 |
| A | PHE170 |
| A | PO4302 |
| A | HOH419 |
| A | HOH456 |
| B | LYS185 |
| site_id | AC7 |
| Number of Residues | 13 |
| Details | binding site for residue GLU B 301 |
| Chain | Residue |
| B | TYR61 |
| B | PRO89 |
| B | LEU90 |
| B | THR91 |
| B | ARG96 |
| B | GLY141 |
| B | SER142 |
| B | THR143 |
| B | GLU193 |
| B | TYR220 |
| B | HOH416 |
| B | HOH499 |
| B | HOH526 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | binding site for residue PO4 B 302 |
| Chain | Residue |
| B | SER140 |
| B | LYS144 |
| B | ARG148 |
| B | HOH434 |
| B | HOH449 |
| B | HOH455 |
| B | HOH502 |
| B | HOH520 |
| B | HOH675 |
| B | HOH678 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 B 303 |
| Chain | Residue |
| B | HIS46 |
| B | LYS240 |
| B | HOH470 |
| B | HOH528 |
| site_id | AD1 |
| Number of Residues | 8 |
| Details | binding site for residue PO4 B 304 |
| Chain | Residue |
| B | ARG203 |
| B | LYS258 |
| B | HOH403 |
| B | HOH413 |
| B | HOH421 |
| B | HOH425 |
| B | HOH619 |
| B | HOH654 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | PRO89 | |
| B | SER142 | |
| B | THR143 | |
| B | GLU193 | |
| A | THR91 | |
| A | ARG96 | |
| A | SER142 | |
| A | THR143 | |
| A | GLU193 | |
| B | PRO89 | |
| B | THR91 | |
| B | ARG96 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | SITE: Interaction with the cone snail toxin Con-ikot-ikot => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ARG64 | |
| A | ARG148 | |
| A | LYS240 | |
| B | ARG64 | |
| B | ARG148 | |
| B | LYS240 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Crucial to convey clamshell closure to channel opening => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ILE121 | |
| B | ILE121 | |
| Chain | Residue | Details |
| A | SER150 | |
| B | SER150 | |
| Chain | Residue | Details |
| A | SER184 | |
| B | SER184 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN3 | |
| B | ASN3 | |
