4Z07
Co-crystal structure of the tandem CNB (CNB-A/B) domains of human PKG I beta with cGMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, C, E) | cGMP-dependent protein kinase 1 | polymer | 262 | 29329.6 | 3 | UniProt (Q13976) Pfam (PF00027) | Homo sapiens (Human) | cGK1,cGMP-dependent protein kinase I,cGKI |
| 2 | D, E, F, G, K (A, C, E) | CYCLIC GUANOSINE MONOPHOSPHATE | non-polymer | 345.2 | 5 | Chemie (PCG) | |||
| 3 | H (C) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | I, J (C) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 2 | Chemie (IPA) | |||
| 5 | L, M, N (A, C, E) | water | water | 18.0 | 330 | Chemie (HOH) |
Sequence modifications
A, C, E: 92 - 351 (UniProt: Q13976)
| PDB | External Database | Details |
|---|---|---|
| Gly 90 | - | expression tag |
| Ser 91 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 87988.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1942.3 | |
| All* | Total formula weight | 89930.9 |
