4Z07
Co-crystal structure of the tandem CNB (CNB-A/B) domains of human PKG I beta with cGMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, C, E) | cGMP-dependent protein kinase 1 | polymer | 262 | 29329.6 | 3 | UniProt (Q13976) Pfam (PF00027) | Homo sapiens (Human) | cGK1,cGMP-dependent protein kinase I,cGKI |
| 2 | D, E, F, G, K (A, C, E) | CYCLIC GUANOSINE MONOPHOSPHATE | non-polymer | 345.2 | 5 | Chemie (PCG) PubChem (177270406) PubChem (136759845) PubChem (135398570) PubChem (135402012) PubChem (135415582) PubChem (135530416) PubChem (135566687) PubChem (135612771) PubChem (136122637) PubChem (136183234) PubChem (136183235) PubChem (136239427) PubChem (136268916) PubChem (136454903) PubChem (136454906) PubChem (136488083) PubChem (136488088) PubChem (136499047) PubChem (136678837) PubChem (137218937) PubChem (137234705) PubChem (137279777) PubChem (138399475) PubChem (164162904) | |||
| 3 | H (C) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | I, J (C) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 2 | Chemie (IPA) | |||
| 5 | L, M, N (A, C, E) | water | water | 18.0 | 330 | Chemie (HOH) |
Sequence modifications
A, C, E: 92 - 351 (UniProt: Q13976)
| PDB | External Database | Details |
|---|---|---|
| Gly 90 | - | expression tag |
| Ser 91 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 87988.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1942.3 | |
| All* | Total formula weight | 89930.9 |
