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4YPM

Crystal structure of a LonA protease domain in complex with bortezomib

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Lon proteasepolymer30332824.51UniProt (A0A059VAZ3)
Pfam (PF22667)
Pfam (PF05362)
Meiothermus taiwanensisATP-dependent protease La
2B
(A)
N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDEnon-polymer384.21Chemie (BO2)
3C
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4D
(A)
DI(HYDROXYETHYL)ETHERnon-polymer106.11Chemie (PEG)
5E
(A)
CITRIC ACIDnon-polymer192.11Chemie (CIT)
6F
(A)
waterwater18.0252Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight32824.5
Non-Polymers*Number of molecules4
Total formula weight706.8
All*Total formula weight33531.3
*Water molecules are not included.

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PDB entries from 2025-06-11

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