4YOL
Human fibroblast growth factor-1 C16S/A66C/C117A/P134A
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Fibroblast growth factor 1 | polymer | 147 | 16775.8 | 2 | UniProt (P05230) Pfam (PF00167) In PDB | Homo sapiens (Human) | FGF-1, Acidic fibroblast growth factor, aFGF, Endothelial cell growth factor, ECGF, Heparin-binding growth factor 1, HBGF-1 |
2 | A, B | CITRATE ANION | non-polymer | 189.1 | 2 | Chemie (FLC) | |||
3 | A | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
4 | water | water | 18.0 | 321 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 140 (UniProt: P05230)
PDB | External Database | Details |
---|---|---|
Met -1 | - | expression tag |
His 0 | - | expression tag |
His 1 | - | expression tag |
His 1 | - | expression tag |
His 1 | - | expression tag |
His 1 | - | expression tag |
His 1 | - | expression tag |
Ser 16 | Cys 31 | engineered mutation |
Cys 66 | Ala 81 | engineered mutation |
Ala 117 | Cys 132 | engineered mutation |
Ala 134 | Pro 149 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 33551.7 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 447.3 | |
All* | Total formula weight | 33999.0 |