4YNQ
TREX1-dsDNA complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Three-prime repair exonuclease 1 | polymer | 235 | 25693.3 | 4 | UniProt (Q91XB0) | Mus musculus (Mouse) | 3'-5' exonuclease TREX1,DNase III |
| 2 | E, G (E, G) | DNA (24-MER) | polymer | 21 | 6449.2 | 2 | synthetic construct | ||
| 3 | F, H (F, H) | DNA (5'-D(P*GP*TP*GP*CP*TP*GP*AP*CP*GP*TP*CP*AP*GP*CP*AP*CP*GP*AP*CP*G)-3') | polymer | 20 | 6160.0 | 2 | synthetic construct | ||
| 4 | I, J, K, L (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) PubChem (888) | |||
| 5 | M (H) | THYMIDINE-5'-PHOSPHATE | non-polymer | 322.2 | 1 | Chemie (TMP) PubChem (1139) PubChem (9700) PubChem (444919) PubChem (5274091) PubChem (5748250) PubChem (129069890) PubChem (133126478) PubChem (18531120) PubChem (23657880) PubChem (24802545) PubChem (25113134) PubChem (44361457) PubChem (51397487) PubChem (164603144) PubChem (10147784) PubChem (20711568) | |||
| 6 | N, O, P, Q, R... (A, B, C, D, E...) | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 235 (UniProt: Q91XB0)
| PDB | External Database | Details |
|---|---|---|
| Asn 18 | Asp 18 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 127991.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 419.4 | |
| All* | Total formula weight | 128411.0 |






