4YNQ
TREX1-dsDNA complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0008408 | molecular_function | 3'-5' exonuclease activity |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0008408 | molecular_function | 3'-5' exonuclease activity |
| C | 0003676 | molecular_function | nucleic acid binding |
| C | 0008408 | molecular_function | 3'-5' exonuclease activity |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0008408 | molecular_function | 3'-5' exonuclease activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 301 |
| Chain | Residue |
| A | ASN18 |
| A | HOH401 |
| E | DC23 |
| E | DG24 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 301 |
| Chain | Residue |
| F | DG24 |
| B | ASN18 |
| B | HOH403 |
| B | HOH406 |
| B | HOH407 |
| F | DC23 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue MG C 301 |
| Chain | Residue |
| C | ASN18 |
| C | HOH403 |
| C | HOH405 |
| H | DC23 |
| H | DG24 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue MG D 301 |
| Chain | Residue |
| D | ASN18 |
| D | HIS124 |
| D | HOH401 |
| G | DC23 |
| G | DG24 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue TMP H 101 |
| Chain | Residue |
| B | ARG128 |
| F | DG21 |
| F | DA22 |
| F | DC23 |
| H | DG21 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"17355961","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17293595","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17355961","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18780819","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22071149","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9NSU2","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
