4YLU

X-ray structure of MERS-CoV nsp5 protease bound with a non-covalent inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	ORF1a protein	polymer	306	33354.2	4	UniProt (A0A0A7E693) Pfam (PF05409) UniProt (by SIFTS) (V9TU12)	Middle East respiratory syndrome coronavirus
2	E, H, K, M (A, B, C, D)	N-{4-[(1H-benzotriazol-1-ylacetyl)(thiophen-3-ylmethyl)amino]phenyl}propanamide	non-polymer		419.5	4	Chemie (R30)
3	F, G, I, J, L... (A, B, C, D)	ACETATE ION	non-polymer		59.0	6	Chemie (ACT)
4	O, P, Q, R (A, B, C, D)	water	water		18.0	995	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	133416.7
Non-Polymers*	Number of molecules	10
	Total formula weight	2032.3
All*	Total formula weight	135448.9

*Water molecules are not included.