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4YJV

THE KINASE DOMAIN OF HUMAN SPLEEN TYROSINE (SYK) IN COMPLEX WITH GTC000250

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tyrosine-protein kinase SYKpolymer28132810.61UniProt (P43405)
Pfam (PF07714)
Homo sapiens (Human)Spleen tyrosine kinase,p72-Syk
2B
(A)
3-[6-({4-[ethyl(1H-indazol-4-yl)amino]-5-fluoropyrimidin-2-yl}amino)-2,4-dihydro-1H-indazol-1-yl]propan-1-olnon-polymer448.51Chemie (4DT)
3C
(A)
waterwater18.0343Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight32810.6
Non-Polymers*Number of molecules1
Total formula weight448.5
All*Total formula weight33259.1
*Water molecules are not included.

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PDB entries from 2025-07-09

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