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4YE2

The 1.35 structure of a viral RNase L antagonist reveals basis for the 2'-5'-oligoadenylate binding and enzyme activity.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Capping enzyme proteinpolymer14416766.52UniProt (B3F2X4)Rotavirus ACapping protein VP3,VP3
2C
(A)
ADENOSINE-2'-5'-DIPHOSPHATEnon-polymer427.21Chemie (A2P)
PubChem (2027)
PubChem (168973)
PubChem (440141)
PubChem (6102530)
PubChem (176478996)
PubChem (92436485)
PubChem (92209724)
PubChem (92209725)
PubChem (92209726)
PubChem (92209727)
PubChem (92450259)
PubChem (92855694)
PubChem (124351419)
3D
(B)
SULFATE IONnon-polymer96.11Chemie (SO4)
4E
(B)
waterwater18.03Chemie (HOH)
Sequence modifications
A, B: 694 - 835 (UniProt: B3F2X4)
PDBExternal DatabaseDetails
Ser 692-expression tag
Gly 693-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight33533.0
Non-Polymers*Number of molecules2
Total formula weight523.3
All*Total formula weight34056.2
*Water molecules are not included.

251801

PDB entries from 2026-04-08

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