4YCV
Crystal structure of cladosporin in complex with plasmodium lysyl-tRNA synthetase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Lysine--tRNA ligase | polymer | 516 | 59781.1 | 4 | UniProt (W7JP72) Pfam (PF01336) Pfam (PF00152) | Plasmodium falciparum (isolate NF54) | Lysyl-tRNA synthetase |
| 2 | E, F, G, H (A, B, C, D) | cladosporin | non-polymer | 292.3 | 4 | Chemie (KRS) PubChem (37269) PubChem (45488860) PubChem (62705396) PubChem (66575611) PubChem (71595470) PubChem (71728346) PubChem (92276885) PubChem (92277885) PubChem (13990016) PubChem (92276887) PubChem (102579672) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 77 - 583 (UniProt: W7JP72)
| PDB | External Database | Details |
|---|---|---|
| Met 76 | - | initiating methionine |
| Gly 584 | - | expression tag |
| Gly 585 | - | expression tag |
| His 586 | - | expression tag |
| His 587 | - | expression tag |
| His 588 | - | expression tag |
| His 589 | - | expression tag |
| His 590 | - | expression tag |
| His 591 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 239124.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1169.3 | |
| All* | Total formula weight | 240293.8 |
