4YC9
Crystal structure of TRIM24 PHD-bromodomain complexed with N-(6-{3-[4-(dimethylamino)butoxy]-5-propoxyphenoxy}-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl)-3,4-dimethoxybenzene-1-sulfonamide (8i)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transcription intermediary factor 1-alpha | polymer | 184 | 21318.4 | 1 | UniProt (O15164) Pfam (PF00628) Pfam (PF00439) | Homo sapiens (Human) | TIF1-alpha,E3 ubiquitin-protein ligase TRIM24,RING finger protein 82,Tripartite motif-containing protein 24 |
| 2 | B, C (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | E (A) | N-(6-{3-[4-(dimethylamino)butoxy]-5-propoxyphenoxy}-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-3,4-dimethoxybenzenesulfonamide | non-polymer | 642.8 | 1 | Chemie (4C1) | |||
| 5 | F (A) | water | water | 18.0 | 214 | Chemie (HOH) |
Sequence modifications
A: 824 - 1006 (UniProt: O15164)
| PDB | External Database | Details |
|---|---|---|
| Ser 823 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21318.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 865.7 | |
| All* | Total formula weight | 22184.1 |
