4YBR

Structure of Mycobacterium tuberculosis NadD in complex with NADP, P21212

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Nicotinate-nucleotide adenylyltransferase	polymer	201	22352.3	2	UniProt (P9WJJ5) Pfam (PF01467) In PDB	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	Deamido-NAD(+) diphosphorylase,Deamido-NAD(+) pyrophosphorylase,Nicotinate mononucleotide adenylyltransferase,NaMN adenylyltransferase
2	A, B	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	2	Chemie (NAP)
3	A, B	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	non-polymer		238.3	2	Chemie (EPE)
4	A, B	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
5	B	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
6		water	water		18.0	339	Chemie (HOH)

Sequence modifications

A, B: 9 - 200 (UniProt: P9WJJ5)

PDB	External Database	Details
Gly 0	-	expression tag
Ala 1	-	expression tag
Met 2	-	expression tag
Gly 3	-	expression tag
Arg 4	-	SEE REMARK 999
Arg 5	-	SEE REMARK 999
Leu 6	-	SEE REMARK 999
Gly 7	-	SEE REMARK 999
Val 8	-	SEE REMARK 999
Arg 196	Cys 188	engineered mutation
Thr 200	Cys 192	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	44704.6
Non-Polymers*	Number of molecules	8
	Total formula weight	2226.5
All*	Total formula weight	46931.0

*Water molecules are not included.