4YBR
Structure of Mycobacterium tuberculosis NadD in complex with NADP, P21212
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nicotinate-nucleotide adenylyltransferase | polymer | 201 | 22352.3 | 2 | UniProt (P9WJJ5) Pfam (PF01467) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | Deamido-NAD(+) diphosphorylase,Deamido-NAD(+) pyrophosphorylase,Nicotinate mononucleotide adenylyltransferase,NaMN adenylyltransferase |
| 2 | C, F (A, B) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 2 | Chemie (NAP) | |||
| 3 | D, G (A, B) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 2 | Chemie (EPE) | |||
| 4 | E, H (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | I, J (B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 6 | K, L (A, B) | water | water | 18.0 | 339 | Chemie (HOH) |
Sequence modifications
A, B: 9 - 200 (UniProt: P9WJJ5)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Ala 1 | - | expression tag |
| Met 2 | - | expression tag |
| Gly 3 | - | expression tag |
| Arg 4 | - | SEE REMARK 999 |
| Arg 5 | - | SEE REMARK 999 |
| Leu 6 | - | SEE REMARK 999 |
| Gly 7 | - | SEE REMARK 999 |
| Val 8 | - | SEE REMARK 999 |
| Arg 196 | Cys 188 | engineered mutation |
| Thr 200 | Cys 192 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 44704.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2226.5 | |
| All* | Total formula weight | 46931.0 |
