4YBR
Structure of Mycobacterium tuberculosis NadD in complex with NADP, P21212
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000309 | molecular_function | nicotinamide-nucleotide adenylyltransferase activity |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004515 | molecular_function | nicotinate-nucleotide adenylyltransferase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009165 | biological_process | nucleotide biosynthetic process |
| A | 0009435 | biological_process | NAD biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0019363 | biological_process | pyridine nucleotide biosynthetic process |
| A | 0070566 | molecular_function | adenylyltransferase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000309 | molecular_function | nicotinamide-nucleotide adenylyltransferase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004515 | molecular_function | nicotinate-nucleotide adenylyltransferase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009165 | biological_process | nucleotide biosynthetic process |
| B | 0009435 | biological_process | NAD biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0019363 | biological_process | pyridine nucleotide biosynthetic process |
| B | 0070566 | molecular_function | adenylyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 28 |
| Details | binding site for residue NAP A 301 |
| Chain | Residue |
| A | MET9 |
| A | PHE104 |
| A | THR106 |
| A | GLY107 |
| A | ALA110 |
| A | ILE114 |
| A | TRP117 |
| A | GLN118 |
| A | VAL132 |
| A | SER167 |
| A | SER168 |
| A | GLY10 |
| A | HOH403 |
| A | HOH409 |
| A | HOH410 |
| A | HOH416 |
| A | HOH417 |
| A | HOH422 |
| A | HOH435 |
| A | HOH511 |
| A | HOH517 |
| A | GLY11 |
| A | THR12 |
| A | HIS17 |
| A | HIS20 |
| A | SER41 |
| A | THR84 |
| A | THR86 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue EPE A 302 |
| Chain | Residue |
| A | TRP182 |
| A | TYR183 |
| A | ASP187 |
| A | HOH451 |
| A | HOH465 |
| A | HOH479 |
| A | HOH483 |
| B | SER67 |
| B | ASN68 |
| B | PRO69 |
| B | ARG70 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | ASN141 |
| A | GLU142 |
| A | HIS143 |
| A | ILE144 |
| A | HOH471 |
| B | LEU151 |
| site_id | AC4 |
| Number of Residues | 27 |
| Details | binding site for residue NAP B 301 |
| Chain | Residue |
| B | MET9 |
| B | GLY10 |
| B | GLY11 |
| B | THR12 |
| B | HIS17 |
| B | HIS20 |
| B | SER41 |
| B | ARG49 |
| B | THR84 |
| B | TYR85 |
| B | THR86 |
| B | PHE104 |
| B | THR106 |
| B | GLY107 |
| B | ALA110 |
| B | ILE114 |
| B | VAL132 |
| B | ARG134 |
| B | SER167 |
| B | SER168 |
| B | SO4303 |
| B | HOH403 |
| B | HOH406 |
| B | HOH410 |
| B | HOH411 |
| B | HOH499 |
| B | HOH527 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | binding site for residue EPE B 302 |
| Chain | Residue |
| A | SER67 |
| A | ASN68 |
| A | PRO69 |
| A | ARG70 |
| B | TRP182 |
| B | TYR183 |
| B | ASP187 |
| B | HOH447 |
| B | HOH458 |
| B | HOH492 |
| B | HOH503 |
| B | HOH513 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 B 303 |
| Chain | Residue |
| B | ARG134 |
| B | TYR137 |
| B | THR169 |
| B | NAP301 |
| B | HOH403 |
| B | HOH419 |
| B | HOH430 |
| B | HOH442 |
| B | HOH529 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 304 |
| Chain | Residue |
| A | GLY82 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 305 |
| Chain | Residue |
| B | ARG4 |
| B | HIS97 |
| B | ASP99 |
| B | SER100 |
