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4Y7R

Crystal structure of WDR5 in complex with MYC MbIIIb peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
WD repeat-containing protein 5polymer31334391.01UniProt (P61964)
Pfam (PF00400)
Homo sapiens (Human)BMP2-induced 3-kb gene protein
2B
(B)
MYC MbIIIb peptidepolymer8889.01UniProt (by SIFTS) (P01106)synthetic construct
3C
(A)
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOLnon-polymer122.11Chemie (TRS)
4D
(A)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
5E, F
(A, B)
waterwater18.0179Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight35280.0
Non-Polymers*Number of molecules2
Total formula weight184.2
All*Total formula weight35464.2
*Water molecules are not included.

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PDB entries from 2024-11-13

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