4Y6O
Human SIRT2 in complex with myristoylated peptide (TNF-alphaK20myr)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | NAD-dependent protein deacetylase sirtuin-2 | polymer | 293 | 33201.2 | 2 | UniProt (Q8IXJ6) Pfam (PF02146) In PDB | Homo sapiens (Human) | Regulatory protein SIR2 homolog 2,SIR2-like protein 2 |
2 | C, D | peptide LEU-PRO-LYS-MYK-THR-GLY-GLY | polymer | 7 | 911.2 | 2 | UniProt (by SIFTS) (P01375) In PDB | Homo sapiens | |
3 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
4 | water | water | 18.0 | 424 | Chemie (HOH) |
Sequence modifications
A, B: 52 - 356 (UniProt: Q8IXJ6)
PDB | External Database | Details |
---|---|---|
- | Gln 292 | deletion |
- | Ser 293 | deletion |
- | Asp 294 | deletion |
- | Pro 295 | deletion |
- | Phe 296 | deletion |
- | Leu 297 | deletion |
- | Gly 298 | deletion |
- | Met 299 | deletion |
- | Ile 300 | deletion |
- | Met 301 | deletion |
- | Gly 302 | deletion |
- | Leu 303 | deletion |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 68224.9 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 130.8 | |
All* | Total formula weight | 68355.7 |